FILE - In this June 12, 2009 file photo, Amanda Knox attends a hearing in the Meredith Kercher murder trial with her lawyer Luciano Ghirga, in Perugia, Italy. Amanda Knox's lawyers have formally asked Italy's court of last resort to review the U.S. student's appeals court conviction for the 2007 stabbing murder of her British roommate on Wednesday, June 18, 2014. Defense lawyer Luciano Ghirga said the paperwork was submitted last Thursday to the Rome-based Court of Cassation. Knox's lawyers had pledged to turn to Italy's top criminal court after a Florence appeals court in January reinstated a lower court's murder convictions of Knox and her Italian former boyfriend in the slaying of Meredith Kercher in Perugia, Italy, where all three were studying. The defense filed its recourse after studying the appeals court's written rationale, issued in April, for the convictions. Cassation judges can either uphold the convictions if they find the appeals trial was properly conducted or order yet another appellate trial. Ghirga said on Wednesday, June 18, 2014, that the Cassation Court might take up the case late this year or in early 2015. (AP Photo/Stefano Medici, file)