The designation is the latest measure in the Trump administration's escalating campaign to combat drug trafficking into the U.S. In previewing the step about a week ago, U.S. Secretary of State Marco Rubio accused Cartel de los Soles, or Cartel of the Suns, of being “responsible for terrorist violence” in the Western Hemisphere. But the entity that the U.S. government alleges is led by Maduro is not a cartel per se.